Modified two-tiered testing algorithm for Lyme disease serology: the Canadian context
Background: 830 Lyme disease (LD) is emerging in many parts of central and eastern Canada.Serological testing is most commonly used to support laboratory diagnosis of LD.Standard two-tiered testing (STTT) for LD involves detection of Borrelia burgdorferi antibodies using an enzyme immunoassay (EIA) followed by IgM and/or IgG immunoblots.However, im